Serine/threonine/tyrosine-interacting protein (STYX)
Homo sapiens — UniProt Q8WUJ0
Data last refreshed: (UniProt release unknown)
Key facts
Serine/threonine/tyrosine-interacting protein (STYX) is a protein from Homo sapiens identified by UniProt accession Q8WUJ0, 223 residues long. MolForge cross-references it against 0 known binders and 107 disease associations.
- UniProt accession: Q8WUJ0; gene symbol STYX.
- Organism: Homo sapiens.
- Length: 223 amino acids.
- Top disease associations (Open Targets): protein measurement, blood protein measurement and azoospermia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine/threonine/tyrosine-interacting protein |
|---|---|
| UniProt accession | Q8WUJ0 |
| Gene | STYX |
| Organism | Homo sapiens |
| Length | 223 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (107)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.24
- blood protein measurement · score 0.16
- azoospermia · score 0.11
- male infertility with teratozoospermia due to single gene mutation · score 0.10
- spermatogenic failure 42 · score 0.09
- spermatogenic failure 72 · score 0.09
- spermatogenic failure 27 · score 0.09
- spermatogenic failure 46 · score 0.09
- spermatogenic failure 18 · score 0.09
- spermatogenic failure 43 · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WUJ0-F1 | alphafold | PREDICTED | 87.24 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WUJ0.
Amino-acid sequence (223 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with STYX?
The strongest Open Targets associations for STYX are protein measurement, blood protein measurement, azoospermia, male infertility with teratozoospermia due to single gene mutation and spermatogenic failure 42.
How long is the STYX protein?
The Homo sapiens STYX protein (UniProt Q8WUJ0) is 223 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WUJ0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WUJ0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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