Neuferricin (CYB5D2)
Homo sapiens — UniProt Q8WUJ1
Data last refreshed: (UniProt release unknown)
Key facts
Neuferricin (CYB5D2) is a protein from Homo sapiens identified by UniProt accession Q8WUJ1, 264 residues long. MolForge cross-references it against 0 known binders and 48 disease associations.
- UniProt accession: Q8WUJ1; gene symbol CYB5D2.
- Organism: Homo sapiens.
- Length: 264 amino acids.
- Top disease associations (Open Targets): hematocrit, type 2 diabetes mellitus and heel bone mineral density.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Neuferricin |
|---|---|
| UniProt accession | Q8WUJ1 |
| Gene | CYB5D2 |
| Organism | Homo sapiens |
| Length | 264 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (48)
Diseases linked to this target (Open Targets).
- hematocrit · score 0.30
- type 2 diabetes mellitus · score 0.17
- heel bone mineral density · score 0.14
- body fat percentage · score 0.14
- waist-hip ratio · score 0.13
- fat body mass · score 0.13
- diastolic blood pressure · score 0.11
- serum albumin measurement · score 0.11
- hypertension · score 0.11
- BMI-adjusted waist circumference · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WUJ1-F1 | alphafold | PREDICTED | 90.57 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WUJ1.
Amino-acid sequence (264 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CYB5D2?
The strongest Open Targets associations for CYB5D2 are hematocrit, type 2 diabetes mellitus, heel bone mineral density, body fat percentage and waist-hip ratio.
How long is the CYB5D2 protein?
The Homo sapiens CYB5D2 protein (UniProt Q8WUJ1) is 264 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WUJ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WUJ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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