Programmed cell death 6-interacting protein (PDCD6IP)
Homo sapiens — UniProt Q8WUM4
Data last refreshed: (UniProt release unknown)
Key facts
Programmed cell death 6-interacting protein (PDCD6IP) is a protein from Homo sapiens identified by UniProt accession Q8WUM4, 868 residues long. MolForge cross-references it against 0 known binders and 116 disease associations.
- UniProt accession: Q8WUM4; gene symbol PDCD6IP.
- Organism: Homo sapiens.
- Length: 868 amino acids.
- Top disease associations (Open Targets): anthrax infection, HIV infection and waist-hip ratio.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Programmed cell death 6-interacting protein |
|---|---|
| UniProt accession | Q8WUM4 |
| Gene | PDCD6IP |
| Organism | Homo sapiens |
| Length | 868 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (116)
Diseases linked to this target (Open Targets).
- anthrax infection · score 0.46
- HIV infection · score 0.46
- waist-hip ratio · score 0.32
- brain measurement · score 0.26
- BMI-adjusted waist-hip ratio · score 0.26
- multiple sclerosis · score 0.24
- demyelinating disease · score 0.24
- cystatin-D measurement · score 0.20
- Microcephaly · score 0.19
- Primary microcephaly · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WUM4-F1 | alphafold | PREDICTED | 83.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WUM4.
Amino-acid sequence (868 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PDCD6IP?
The strongest Open Targets associations for PDCD6IP are anthrax infection, HIV infection, waist-hip ratio, brain measurement and BMI-adjusted waist-hip ratio.
How long is the PDCD6IP protein?
The Homo sapiens PDCD6IP protein (UniProt Q8WUM4) is 868 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WUM4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WUM4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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