Sodium-dependent phosphate transporter 1 (SLC20A1)
Homo sapiens — UniProt Q8WUM9
Data last refreshed: (UniProt release unknown)
Key facts
Sodium-dependent phosphate transporter 1 (SLC20A1) is a protein from Homo sapiens identified by UniProt accession Q8WUM9, 679 residues long. MolForge cross-references it against 0 known binders and 298 disease associations.
- UniProt accession: Q8WUM9; gene symbol SLC20A1.
- Organism: Homo sapiens.
- Length: 679 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): neurodegenerative disease, amenorrhea and response to antineoplastic agent.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sodium-dependent phosphate transporter 1 |
|---|---|
| UniProt accession | Q8WUM9 |
| Gene | SLC20A1 |
| Organism | Homo sapiens |
| Length | 679 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (298)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.32
- amenorrhea · score 0.21
- response to antineoplastic agent · score 0.21
- Blackfan-Diamond anemia · score 0.10
- hemoglobin D disease · score 0.08
- head and neck squamous cell carcinoma · score 0.07
- Alpha-thalassemia - intellectual disability syndrome linked to chromosome 16 · score 0.07
- alpha thalassemia-intellectual disability syndrome type 1 · score 0.07
- Congenital dyserythropoietic anemia type I · score 0.07
- Heinz body anemia · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WUM9-F1 | alphafold | PREDICTED | 70.26 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WUM9.
Amino-acid sequence (679 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC20A1?
The strongest Open Targets associations for SLC20A1 are neurodegenerative disease, amenorrhea, response to antineoplastic agent, Blackfan-Diamond anemia and hemoglobin D disease.
How long is the SLC20A1 protein?
The Homo sapiens SLC20A1 protein (UniProt Q8WUM9) is 679 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WUM9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WUM9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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