Ubiquitin domain-containing protein 2 (UBTD2)
Homo sapiens — UniProt Q8WUN7
Data last refreshed: (UniProt release unknown)
Key facts
Ubiquitin domain-containing protein 2 (UBTD2) is a protein from Homo sapiens identified by UniProt accession Q8WUN7, 234 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q8WUN7; gene symbol UBTD2.
- Organism: Homo sapiens.
- Length: 234 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, PHF-tau measurement and BMI-adjusted waist-hip ratio.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubiquitin domain-containing protein 2 |
|---|---|
| UniProt accession | Q8WUN7 |
| Gene | UBTD2 |
| Organism | Homo sapiens |
| Length | 234 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.26
- PHF-tau measurement · score 0.21
- BMI-adjusted waist-hip ratio · score 0.03
- waist-hip ratio · score 0.03
- neoplasm · score 0.01
- chronic myelogenous leukemia · score 0.01
- Sepsis · score 0.01
- Frontotemporal dementia · score 0.00
- X-linked hyper-IgM syndrome · score 0.00
- astrocytoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WUN7-F1 | alphafold | PREDICTED | 70.40 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WUN7.
Amino-acid sequence (234 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UBTD2?
The strongest Open Targets associations for UBTD2 are neurodegenerative disease, PHF-tau measurement, BMI-adjusted waist-hip ratio, waist-hip ratio and neoplasm.
How long is the UBTD2 protein?
The Homo sapiens UBTD2 protein (UniProt Q8WUN7) is 234 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WUN7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WUN7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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