Splicing factor Cactin (CACTIN)
Homo sapiens — UniProt Q8WUQ7
Data last refreshed: (UniProt release unknown)
Key facts
Splicing factor Cactin (CACTIN) is a protein from Homo sapiens identified by UniProt accession Q8WUQ7, 758 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.
- UniProt accession: Q8WUQ7; gene symbol CACTIN.
- Organism: Homo sapiens.
- Length: 758 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, lymphocyte count and Meacham syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Splicing factor Cactin |
|---|---|
| UniProt accession | Q8WUQ7 |
| Gene | CACTIN |
| Organism | Homo sapiens |
| Length | 758 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- lymphocyte count · score 0.10
- Meacham syndrome · score 0.03
- Isolated follicle stimulating hormone deficiency · score 0.03
- idiopathic hypereosinophilic syndrome · score 0.03
- fat body mass · score 0.03
- breast cancer · score 0.01
- gonorrhea · score 0.01
- Dilated cardiomyopathy · score 0.01
- infect · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WUQ7-F1 | alphafold | PREDICTED | 68.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WUQ7.
Amino-acid sequence (758 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CACTIN?
The strongest Open Targets associations for CACTIN are neurodegenerative disease, lymphocyte count, Meacham syndrome, Isolated follicle stimulating hormone deficiency and idiopathic hypereosinophilic syndrome.
How long is the CACTIN protein?
The Homo sapiens CACTIN protein (UniProt Q8WUQ7) is 758 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WUQ7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WUQ7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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