UPF0235 protein C15orf40 (C15orf40)
Homo sapiens — UniProt Q8WUR7
Data last refreshed: (UniProt release unknown)
Key facts
UPF0235 protein C15orf40 (C15orf40) is a protein from Homo sapiens identified by UniProt accession Q8WUR7, 153 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q8WUR7; gene symbol C15orf40.
- Organism: Homo sapiens.
- Length: 153 amino acids.
- Top disease associations (Open Targets): diastolic blood pressure, bipolar disorder and smoking status measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | UPF0235 protein C15orf40 |
|---|---|
| UniProt accession | Q8WUR7 |
| Gene | C15orf40 |
| Organism | Homo sapiens |
| Length | 153 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- diastolic blood pressure · score 0.28
- bipolar disorder · score 0.20
- smoking status measurement · score 0.14
- smoking initiation · score 0.10
- basophil percentage of leukocytes · score 0.07
- chronic obstructive pulmonary disease · score 0.05
- basophil count · score 0.04
- diet measurement · score 0.04
- platelet crit · score 0.03
- antisocial behaviour measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WUR7-F1 | alphafold | PREDICTED | 75.61 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WUR7.
Amino-acid sequence (153 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C15orf40?
The strongest Open Targets associations for C15orf40 are diastolic blood pressure, bipolar disorder, smoking status measurement, smoking initiation and basophil percentage of leukocytes.
How long is the C15orf40 protein?
The Homo sapiens C15orf40 protein (UniProt Q8WUR7) is 153 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WUR7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WUR7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.