Sodium-coupled neutral amino acid transporter 5 (SLC38A5)
Homo sapiens — UniProt Q8WUX1
Data last refreshed: (UniProt release unknown)
Key facts
Sodium-coupled neutral amino acid transporter 5 (SLC38A5) is a protein from Homo sapiens identified by UniProt accession Q8WUX1, 472 residues long. MolForge cross-references it against 0 known binders and 58 disease associations.
- UniProt accession: Q8WUX1; gene symbol SLC38A5.
- Organism: Homo sapiens.
- Length: 472 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): erythrocyte count, mean corpuscular hemoglobin and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sodium-coupled neutral amino acid transporter 5 |
|---|---|
| UniProt accession | Q8WUX1 |
| Gene | SLC38A5 |
| Organism | Homo sapiens |
| Length | 472 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (58)
Diseases linked to this target (Open Targets).
- erythrocyte count · score 0.23
- mean corpuscular hemoglobin · score 0.23
- mean corpuscular volume · score 0.23
- total blood protein measurement · score 0.23
- Abnormality of neuronal migration · score 0.11
- neoplasm · score 0.09
- pancreatic neoplasm · score 0.07
- triple-negative breast cancer · score 0.07
- acute lymphoblastic leukemia · score 0.06
- breast cancer · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WUX1-F1 | alphafold | PREDICTED | 79.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WUX1.
Amino-acid sequence (472 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC38A5?
The strongest Open Targets associations for SLC38A5 are erythrocyte count, mean corpuscular hemoglobin, mean corpuscular volume, total blood protein measurement and Abnormality of neuronal migration.
How long is the SLC38A5 protein?
The Homo sapiens SLC38A5 protein (UniProt Q8WUX1) is 472 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WUX1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WUX1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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