Protein THEM6 (THEM6)
Homo sapiens — UniProt Q8WUY1
Data last refreshed: (UniProt release unknown)
Key facts
Protein THEM6 (THEM6) is a protein from Homo sapiens identified by UniProt accession Q8WUY1, 208 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.
- UniProt accession: Q8WUY1; gene symbol THEM6.
- Organism: Homo sapiens.
- Length: 208 amino acids.
- Top disease associations (Open Targets): body fat percentage, total blood protein measurement and fat body mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein THEM6 |
|---|---|
| UniProt accession | Q8WUY1 |
| Gene | THEM6 |
| Organism | Homo sapiens |
| Length | 208 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (32)
Diseases linked to this target (Open Targets).
- body fat percentage · score 0.24
- total blood protein measurement · score 0.17
- fat body mass · score 0.15
- calcium measurement · score 0.15
- optic disc size measurement · score 0.13
- serum albumin measurement · score 0.10
- DNA methylation · score 0.09
- neoplasm · score 0.09
- cancer · score 0.08
- Malignant Urinary System Neoplasm · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WUY1-F1 | alphafold | PREDICTED | 94.88 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WUY1.
Amino-acid sequence (208 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with THEM6?
The strongest Open Targets associations for THEM6 are body fat percentage, total blood protein measurement, fat body mass, calcium measurement and optic disc size measurement.
How long is the THEM6 protein?
The Homo sapiens THEM6 protein (UniProt Q8WUY1) is 208 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WUY1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WUY1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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