Probable N-acetyltransferase 14 (NAT14)
Homo sapiens — UniProt Q8WUY8
Data last refreshed: (UniProt release unknown)
Key facts
Probable N-acetyltransferase 14 (NAT14) is a protein from Homo sapiens identified by UniProt accession Q8WUY8, 206 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q8WUY8; gene symbol NAT14.
- Organism: Homo sapiens.
- Length: 206 amino acids.
- Top disease associations (Open Targets): BMI-adjusted waist-hip ratio, waist-hip ratio and lean body mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Probable N-acetyltransferase 14 |
|---|---|
| UniProt accession | Q8WUY8 |
| Gene | NAT14 |
| Organism | Homo sapiens |
| Length | 206 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist-hip ratio · score 0.15
- waist-hip ratio · score 0.10
- lean body mass · score 0.08
- forced expiratory volume · score 0.07
- appendicular lean mass · score 0.06
- whole body water mass · score 0.06
- body height · score 0.05
- vital capacity · score 0.05
- base metabolic rate measurement · score 0.05
- fat body mass · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WUY8-F1 | alphafold | PREDICTED | 83.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WUY8.
Amino-acid sequence (206 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NAT14?
The strongest Open Targets associations for NAT14 are BMI-adjusted waist-hip ratio, waist-hip ratio, lean body mass, forced expiratory volume and appendicular lean mass.
How long is the NAT14 protein?
The Homo sapiens NAT14 protein (UniProt Q8WUY8) is 206 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WUY8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WUY8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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