DEP domain-containing protein 1B (DEPDC1B)
Homo sapiens — UniProt Q8WUY9
Data last refreshed: (UniProt release unknown)
Key facts
DEP domain-containing protein 1B (DEPDC1B) is a protein from Homo sapiens identified by UniProt accession Q8WUY9, 529 residues long. MolForge cross-references it against 0 known binders and 83 disease associations.
- UniProt accession: Q8WUY9; gene symbol DEPDC1B.
- Organism: Homo sapiens.
- Length: 529 amino acids.
- Top disease associations (Open Targets): self reported educational attainment, intelligence and phosphatidylethanolamine measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | DEP domain-containing protein 1B |
|---|---|
| UniProt accession | Q8WUY9 |
| Gene | DEPDC1B |
| Organism | Homo sapiens |
| Length | 529 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (83)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.34
- intelligence · score 0.24
- phosphatidylethanolamine measurement · score 0.21
- mathematical ability · score 0.17
- coffee consumption · score 0.15
- mean platelet volume · score 0.14
- mean corpuscular volume · score 0.14
- acrodysostosis 2 with or without hormone resistance · score 0.12
- hepatocellular carcinoma · score 0.10
- neoplasm · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WUY9-F1 | alphafold | PREDICTED | 77.71 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WUY9.
Amino-acid sequence (529 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DEPDC1B?
The strongest Open Targets associations for DEPDC1B are self reported educational attainment, intelligence, phosphatidylethanolamine measurement, mathematical ability and coffee consumption.
How long is the DEPDC1B protein?
The Homo sapiens DEPDC1B protein (UniProt Q8WUY9) is 529 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WUY9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WUY9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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