B-cell CLL/lymphoma 7 protein family member C (BCL7C)
Homo sapiens — UniProt Q8WUZ0
Data last refreshed: (UniProt release unknown)
Key facts
B-cell CLL/lymphoma 7 protein family member C (BCL7C) is a protein from Homo sapiens identified by UniProt accession Q8WUZ0, 217 residues long. MolForge cross-references it against 0 known binders and 48 disease associations.
- UniProt accession: Q8WUZ0; gene symbol BCL7C.
- Organism: Homo sapiens.
- Length: 217 amino acids.
- Top disease associations (Open Targets): serum non-albumin protein measurement, HMG CoA reductase inhibitor use measurement and HbA1c measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | B-cell CLL/lymphoma 7 protein family member C |
|---|---|
| UniProt accession | Q8WUZ0 |
| Gene | BCL7C |
| Organism | Homo sapiens |
| Length | 217 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (48)
Diseases linked to this target (Open Targets).
- serum non-albumin protein measurement · score 0.10
- HMG CoA reductase inhibitor use measurement · score 0.08
- HbA1c measurement · score 0.07
- Hypercholesterolemia · score 0.07
- monocyte count · score 0.07
- vitamin D measurement · score 0.06
- leukocyte count · score 0.06
- platelet count · score 0.06
- vital capacity · score 0.06
- hypoparathyroidism, familial isolated, 2 · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WUZ0-F1 | alphafold | PREDICTED | 62.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WUZ0.
Amino-acid sequence (217 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BCL7C?
The strongest Open Targets associations for BCL7C are serum non-albumin protein measurement, HMG CoA reductase inhibitor use measurement, HbA1c measurement, Hypercholesterolemia and monocyte count.
How long is the BCL7C protein?
The Homo sapiens BCL7C protein (UniProt Q8WUZ0) is 217 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WUZ0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WUZ0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.