AN1-type zinc finger protein 2B (ZFAND2B)
Homo sapiens — UniProt Q8WV99
Data last refreshed: (UniProt release unknown)
Key facts
AN1-type zinc finger protein 2B (ZFAND2B) is a protein from Homo sapiens identified by UniProt accession Q8WV99, 257 residues long. MolForge cross-references it against 0 known binders and 204 disease associations.
- UniProt accession: Q8WV99; gene symbol ZFAND2B.
- Organism: Homo sapiens.
- Length: 257 amino acids.
- Top disease associations (Open Targets): Red cell distribution width, mean reticulocyte volume and monocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | AN1-type zinc finger protein 2B |
|---|---|
| UniProt accession | Q8WV99 |
| Gene | ZFAND2B |
| Organism | Homo sapiens |
| Length | 257 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (204)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.11
- mean reticulocyte volume · score 0.10
- monocyte count · score 0.08
- mean corpuscular volume · score 0.07
- leukocyte count · score 0.07
- body height · score 0.06
- neutrophil count · score 0.06
- transient myeloproliferative syndrome · score 0.06
- neutrophil immunodeficiency syndrome · score 0.06
- triglyceride measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WV99-F1 | alphafold | PREDICTED | 75.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WV99.
Amino-acid sequence (257 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZFAND2B?
The strongest Open Targets associations for ZFAND2B are Red cell distribution width, mean reticulocyte volume, monocyte count, mean corpuscular volume and leukocyte count.
How long is the ZFAND2B protein?
The Homo sapiens ZFAND2B protein (UniProt Q8WV99) is 257 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WV99 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WV99 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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