NudC domain-containing protein 2 (NUDCD2)
Homo sapiens — UniProt Q8WVJ2
Data last refreshed: (UniProt release unknown)
Key facts
NudC domain-containing protein 2 (NUDCD2) is a protein from Homo sapiens identified by UniProt accession Q8WVJ2, 157 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: Q8WVJ2; gene symbol NUDCD2.
- Organism: Homo sapiens.
- Length: 157 amino acids.
- Top disease associations (Open Targets): sex hormone-binding globulin measurement, ceramide measurement and age-related hearing impairment.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | NudC domain-containing protein 2 |
|---|---|
| UniProt accession | Q8WVJ2 |
| Gene | NUDCD2 |
| Organism | Homo sapiens |
| Length | 157 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.25
- ceramide measurement · score 0.21
- age-related hearing impairment · score 0.18
- aortic vascular smooth muscle cell proliferation measurement · score 0.17
- age at first sexual intercourse measurement · score 0.15
- amyloid-beta measurement · score 0.14
- antisocial behaviour measurement · score 0.12
- attention deficit hyperactivity disorder · score 0.12
- substance abuse · score 0.12
- genetic disorder · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WVJ2-F1 | alphafold | PREDICTED | 83.47 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WVJ2.
Amino-acid sequence (157 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NUDCD2?
The strongest Open Targets associations for NUDCD2 are sex hormone-binding globulin measurement, ceramide measurement, age-related hearing impairment, aortic vascular smooth muscle cell proliferation measurement and age at first sexual intercourse measurement.
How long is the NUDCD2 protein?
The Homo sapiens NUDCD2 protein (UniProt Q8WVJ2) is 157 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WVJ2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WVJ2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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