Secreted and transmembrane protein 1 (SECTM1)
Homo sapiens — UniProt Q8WVN6
Data last refreshed: (UniProt release unknown)
Key facts
Secreted and transmembrane protein 1 (SECTM1) is a protein from Homo sapiens identified by UniProt accession Q8WVN6, 248 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.
- UniProt accession: Q8WVN6; gene symbol SECTM1.
- Organism: Homo sapiens.
- Length: 248 amino acids.
- Top disease associations (Open Targets): blood protein measurement, neurodegenerative disease and monocyte percentage of leukocytes.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Secreted and transmembrane protein 1 |
|---|---|
| UniProt accession | Q8WVN6 |
| Gene | SECTM1 |
| Organism | Homo sapiens |
| Length | 248 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (46)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.29
- neurodegenerative disease · score 0.20
- monocyte percentage of leukocytes · score 0.17
- fatty acid measurement · score 0.14
- neoplasm · score 0.10
- glioblastoma multiforme · score 0.08
- cancer · score 0.06
- metabolite measurement · score 0.04
- granulocyte percentage of myeloid white cells · score 0.03
- glioblastoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WVN6-F1 | alphafold | PREDICTED | 74.71 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WVN6.
Amino-acid sequence (248 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SECTM1?
The strongest Open Targets associations for SECTM1 are blood protein measurement, neurodegenerative disease, monocyte percentage of leukocytes, fatty acid measurement and neoplasm.
How long is the SECTM1 protein?
The Homo sapiens SECTM1 protein (UniProt Q8WVN6) is 248 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WVN6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WVN6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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