Ubiquitin-conjugating enzyme E2 Q2 (UBE2Q2)
Homo sapiens — UniProt Q8WVN8
Data last refreshed: (UniProt release unknown)
Key facts
Ubiquitin-conjugating enzyme E2 Q2 (UBE2Q2) is a protein from Homo sapiens identified by UniProt accession Q8WVN8, 375 residues long. MolForge cross-references it against 0 known binders and 66 disease associations.
- UniProt accession: Q8WVN8; gene symbol UBE2Q2.
- Organism: Homo sapiens.
- Length: 375 amino acids.
- Top disease associations (Open Targets): urate measurement, creatinine measurement and glomerular filtration rate.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubiquitin-conjugating enzyme E2 Q2 |
|---|---|
| UniProt accession | Q8WVN8 |
| Gene | UBE2Q2 |
| Organism | Homo sapiens |
| Length | 375 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (66)
Diseases linked to this target (Open Targets).
- urate measurement · score 0.43
- creatinine measurement · score 0.42
- glomerular filtration rate · score 0.39
- cystatin C measurement · score 0.36
- serum urea measurement · score 0.36
- erythrocyte count · score 0.36
- hemoglobin measurement · score 0.35
- gout · score 0.31
- chronic kidney disease · score 0.29
- hematocrit · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WVN8-F1 | alphafold | PREDICTED | 83.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WVN8.
Amino-acid sequence (375 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UBE2Q2?
The strongest Open Targets associations for UBE2Q2 are urate measurement, creatinine measurement, glomerular filtration rate, cystatin C measurement and serum urea measurement.
How long is the UBE2Q2 protein?
The Homo sapiens UBE2Q2 protein (UniProt Q8WVN8) is 375 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WVN8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WVN8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.