Soluble calcium-activated nucleotidase 1 (CANT1)
Homo sapiens — UniProt Q8WVQ1
Data last refreshed: (UniProt release unknown)
Key facts
Soluble calcium-activated nucleotidase 1 (CANT1) is a protein from Homo sapiens identified by UniProt accession Q8WVQ1, 401 residues long. MolForge cross-references it against 0 known binders and 323 disease associations.
- UniProt accession: Q8WVQ1; gene symbol CANT1.
- Organism: Homo sapiens.
- Length: 401 amino acids.
- Top disease associations (Open Targets): Desbuquois syndrome, multiple epiphyseal dysplasia and genetic disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Soluble calcium-activated nucleotidase 1 |
|---|---|
| UniProt accession | Q8WVQ1 |
| Gene | CANT1 |
| Organism | Homo sapiens |
| Length | 401 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (323)
Diseases linked to this target (Open Targets).
- Desbuquois syndrome · score 0.82
- multiple epiphyseal dysplasia · score 0.59
- genetic disorder · score 0.47
- prostate adenocarcinoma · score 0.28
- Abnormality of the skeletal system · score 0.27
- Joint dislocation · score 0.27
- Short stature · score 0.27
- blood protein measurement · score 0.25
- hepatocellular carcinoma · score 0.20
- lung adenocarcinoma · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WVQ1-F1 | alphafold | PREDICTED | 89.43 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WVQ1.
Amino-acid sequence (401 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CANT1?
The strongest Open Targets associations for CANT1 are Desbuquois syndrome, multiple epiphyseal dysplasia, genetic disorder, prostate adenocarcinoma and Abnormality of the skeletal system.
How long is the CANT1 protein?
The Homo sapiens CANT1 protein (UniProt Q8WVQ1) is 401 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WVQ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WVQ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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