Butyrophilin subfamily 2 member A2 (BTN2A2)
Homo sapiens — UniProt Q8WVV5
Data last refreshed: (UniProt release unknown)
Key facts
Butyrophilin subfamily 2 member A2 (BTN2A2) is a protein from Homo sapiens identified by UniProt accession Q8WVV5, 523 residues long. MolForge cross-references it against 0 known binders and 157 disease associations.
- UniProt accession: Q8WVV5; gene symbol BTN2A2.
- Organism: Homo sapiens.
- Length: 523 amino acids.
- Top disease associations (Open Targets): reticulocyte count, reticulocyte measurement and smoking status measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Butyrophilin subfamily 2 member A2 |
|---|---|
| UniProt accession | Q8WVV5 |
| Gene | BTN2A2 |
| Organism | Homo sapiens |
| Length | 523 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (157)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.34
- reticulocyte measurement · score 0.27
- smoking status measurement · score 0.24
- mathematical ability · score 0.20
- genetic disorder · score 0.15
- Red cell distribution width · score 0.13
- thyroid disease · score 0.13
- cutaneous melanoma · score 0.12
- smoking initiation · score 0.11
- diet measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WVV5-F1 | alphafold | PREDICTED | 86.04 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WVV5.
Amino-acid sequence (523 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BTN2A2?
The strongest Open Targets associations for BTN2A2 are reticulocyte count, reticulocyte measurement, smoking status measurement, mathematical ability and genetic disorder.
How long is the BTN2A2 protein?
The Homo sapiens BTN2A2 protein (UniProt Q8WVV5) is 523 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WVV5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WVV5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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