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Heterogeneous nuclear ribonucleoprotein L-like (HNRNPLL)

Homo sapiens — UniProt Q8WVV9

Gene: HNRNPLLHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Heterogeneous nuclear ribonucleoprotein L-like (HNRNPLL) is a protein from Homo sapiens identified by UniProt accession Q8WVV9, 542 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.

  • UniProt accession: Q8WVV9; gene symbol HNRNPLL.
  • Organism: Homo sapiens.
  • Length: 542 amino acids.
  • Top disease associations (Open Targets): body height, lymphocyte count and body mass index.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameHeterogeneous nuclear ribonucleoprotein L-like
UniProt accessionQ8WVV9
GeneHNRNPLL
OrganismHomo sapiens
Length542 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (63)

Diseases linked to this target (Open Targets).

  • body height · score 0.33
  • lymphocyte count · score 0.33
  • body mass index · score 0.28
  • Red cell distribution width · score 0.22
  • hip bone size · score 0.18
  • hip bone mineral density · score 0.18
  • monocyte count · score 0.06
  • common variable immunodeficiency · score 0.05
  • classic Hodgkin lymphoma · score 0.05
  • Hodgkins lymphoma · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8WVV9-F1alphafoldPREDICTED75.68—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WVV9.

Amino-acid sequence (542 residues)

MSSSSSSPRE TYEEDREYES QAKRLKTEEG EIDYSAEEGE NRREATPRGG GDGGGGGRSF SQPEAGGSHH KVSVSPVVHV RGLCESVVEA DLVEALEKFG TICYVMMMPF KRQALVEFEN IDSAKECVTF AADEPVYIAG QQAFFNYSTS KRITRPGNTD DPSGGNKVLL LSIQNPLYPI TVDVLYTVCN PVGKVQRIVI FKRNGIQAMV EFESVLCAQK AKAALNGADI YAGCCTLKIE YARPTRLNVI RNDNDSWDYT KPYLGRRDRG KGRQRQAILG EHPSSFRHDG YGSHGPLLPL PSRYRMGSRD TPELVAYPLP QASSSYMHGG NPSGSVVMVS GLHQLKMNCS RVFNLFCLYG NIEKVKFMKT IPGTALVEMG DEYAVERAVT HLNNVKLFGK RLNVCVSKQH SVVPSQIFEL EDGTSSYKDF AMSKNNRFTS AGQASKNIIQ PPSCVLHYYN VPLCVTEETF TKLCNDHEVL TFIKYKVFDA KPSAKTLSGL LEWECKTDAV EALTALNHYQ IRVPNGSNPY TLKLCFSTSS HL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with HNRNPLL?

The strongest Open Targets associations for HNRNPLL are body height, lymphocyte count, body mass index, Red cell distribution width and hip bone size.

How long is the HNRNPLL protein?

The Homo sapiens HNRNPLL protein (UniProt Q8WVV9) is 542 amino acids long.

Browse: Targets: H · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8WVV9
GeneHNRNPLL
OrganismHomo sapiens
Length542
Binders0
Diseases63
View on UniProt