Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator ARLN (ARLN)
Homo sapiens — UniProt Q8WVX3
Data last refreshed: (UniProt release unknown)
Key facts
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator ARLN (ARLN) is a protein from Homo sapiens identified by UniProt accession Q8WVX3, 66 residues long. MolForge cross-references it against 0 known binders and 68 disease associations.
- UniProt accession: Q8WVX3; gene symbol ARLN.
- Organism: Homo sapiens.
- Length: 66 amino acids.
- Top disease associations (Open Targets): BMI-adjusted waist circumference, BMI-adjusted waist-hip ratio and Immature Reticulocyte Fraction Measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator ARLN |
|---|---|
| UniProt accession | Q8WVX3 |
| Gene | ARLN |
| Organism | Homo sapiens |
| Length | 66 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (68)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist circumference · score 0.13
- BMI-adjusted waist-hip ratio · score 0.11
- Immature Reticulocyte Fraction Measurement · score 0.11
- appendicular lean mass · score 0.11
- total cholesterol measurement · score 0.09
- mean corpuscular volume · score 0.08
- waist-hip ratio · score 0.08
- facial morphology measurement · score 0.08
- lean body mass · score 0.08
- mean reticulocyte volume · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WVX3-F1 | alphafold | PREDICTED | 66.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WVX3.
Amino-acid sequence (66 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ARLN?
The strongest Open Targets associations for ARLN are BMI-adjusted waist circumference, BMI-adjusted waist-hip ratio, Immature Reticulocyte Fraction Measurement, appendicular lean mass and total cholesterol measurement.
How long is the ARLN protein?
The Homo sapiens ARLN protein (UniProt Q8WVX3) is 66 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WVX3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WVX3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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