Fatty acyl-CoA reductase 1 (FAR1)
Homo sapiens — UniProt Q8WVX9
Data last refreshed: (UniProt release unknown)
Key facts
Fatty acyl-CoA reductase 1 (FAR1) is a protein from Homo sapiens identified by UniProt accession Q8WVX9, 515 residues long. MolForge cross-references it against 0 known binders and 164 disease associations.
- UniProt accession: Q8WVX9; gene symbol FAR1.
- Organism: Homo sapiens.
- Length: 515 amino acids.
- Top disease associations (Open Targets): fatty acyl-CoA reductase 1 deficiency, protein measurement and genetic disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Fatty acyl-CoA reductase 1 |
|---|---|
| UniProt accession | Q8WVX9 |
| Gene | FAR1 |
| Organism | Homo sapiens |
| Length | 515 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (164)
Diseases linked to this target (Open Targets).
- fatty acyl-CoA reductase 1 deficiency · score 0.76
- protein measurement · score 0.22
- genetic disorder · score 0.19
- azoospermia · score 0.07
- Gorham-Stout disease · score 0.07
- cancer · score 0.06
- male infertility with teratozoospermia due to single gene mutation · score 0.06
- partial chromosome Y deletion · score 0.06
- dacryocystitis-osteopoikilosis syndrome · score 0.06
- melorheostosis · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WVX9-F1 | alphafold | PREDICTED | 94.22 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WVX9.
Amino-acid sequence (515 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAR1?
The strongest Open Targets associations for FAR1 are fatty acyl-CoA reductase 1 deficiency, protein measurement, genetic disorder, azoospermia and Gorham-Stout disease.
How long is the FAR1 protein?
The Homo sapiens FAR1 protein (UniProt Q8WVX9) is 515 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WVX9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WVX9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.