Ubiquitin-like domain-containing CTD phosphatase 1 (UBLCP1)
Homo sapiens — UniProt Q8WVY7
Data last refreshed: (UniProt release unknown)
Key facts
Ubiquitin-like domain-containing CTD phosphatase 1 (UBLCP1) is a protein from Homo sapiens identified by UniProt accession Q8WVY7, 318 residues long. MolForge cross-references it against 0 known binders and 119 disease associations.
- UniProt accession: Q8WVY7; gene symbol UBLCP1.
- Organism: Homo sapiens.
- Length: 318 amino acids.
- Top disease associations (Open Targets): psoriasis, neurodegenerative disease and tuberculosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubiquitin-like domain-containing CTD phosphatase 1 |
|---|---|
| UniProt accession | Q8WVY7 |
| Gene | UBLCP1 |
| Organism | Homo sapiens |
| Length | 318 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (119)
Diseases linked to this target (Open Targets).
- psoriasis · score 0.43
- neurodegenerative disease · score 0.37
- tuberculosis · score 0.29
- psoriatic arthritis · score 0.25
- drug use measurement · score 0.24
- blood urea nitrogen measurement · score 0.21
- skin disease · score 0.15
- cutaneous psoriasis measurement · score 0.14
- psoriasis vulgaris · score 0.10
- Crohn's disease · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WVY7-F1 | alphafold | PREDICTED | 90.23 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WVY7.
Amino-acid sequence (318 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UBLCP1?
The strongest Open Targets associations for UBLCP1 are psoriasis, neurodegenerative disease, tuberculosis, psoriatic arthritis and drug use measurement.
How long is the UBLCP1 protein?
The Homo sapiens UBLCP1 protein (UniProt Q8WVY7) is 318 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WVY7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WVY7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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