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Palmitoyltransferase ZDHHC19 (ZDHHC19)

Homo sapiens — UniProt Q8WVZ1

Gene: ZDHHC19Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Palmitoyltransferase ZDHHC19 (ZDHHC19) is a protein from Homo sapiens identified by UniProt accession Q8WVZ1, 309 residues long. MolForge cross-references it against 0 known binders and 143 disease associations.

  • UniProt accession: Q8WVZ1; gene symbol ZDHHC19.
  • Organism: Homo sapiens.
  • Length: 309 amino acids.
  • Top disease associations (Open Targets): mean corpuscular hemoglobin concentration, mean corpuscular volume and mean corpuscular hemoglobin.
  • 3D structure: AlphaFold model available.

Target properties

Protein namePalmitoyltransferase ZDHHC19
UniProt accessionQ8WVZ1
GeneZDHHC19
OrganismHomo sapiens
Length309 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (143)

Diseases linked to this target (Open Targets).

  • mean corpuscular hemoglobin concentration · score 0.42
  • mean corpuscular volume · score 0.40
  • mean corpuscular hemoglobin · score 0.39
  • erythrocyte count · score 0.37
  • Red cell distribution width · score 0.33
  • reticulocyte count · score 0.33
  • HbA1c measurement · score 0.28
  • red blood cell density measurement · score 0.27
  • reticulocyte measurement · score 0.27
  • platelet count · score 0.24

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8WVZ1-F1alphafoldPREDICTED78.03—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WVZ1.

Amino-acid sequence (309 residues)

MTLLTDATPL VKEPHPLPLV PRPWFLPSLF AAFNVVLLVF FSGLFFAFPC RWLAQNGEWA FPVITGSLFV LTFFSLVSLN FSDPGILHQG SAEQGPLTVH VVWVNHGAFR LQWCPKCCFH RPPRTYHCPW CNICVEDFDH HCKWVNNCIG HRNFRFFMLL VLSLCLYSGA MLVTCLIFLV RTTHLPFSTD KAIAIVVAVS AAGLLVPLSL LLLIQALSVS SADRTYKGKC RHLQGYNPFD QGCASNWYLT ICAPLGPKYM AEAVQLQRVV GPDWTSMPNL HPPMSPSALN PPAPTSGSLQ SREGTPGAW

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZDHHC19?

The strongest Open Targets associations for ZDHHC19 are mean corpuscular hemoglobin concentration, mean corpuscular volume, mean corpuscular hemoglobin, erythrocyte count and Red cell distribution width.

How long is the ZDHHC19 protein?

The Homo sapiens ZDHHC19 protein (UniProt Q8WVZ1) is 309 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8WVZ1
GeneZDHHC19
OrganismHomo sapiens
Length309
Binders0
Diseases143
View on UniProt