Palmitoyltransferase ZDHHC19 (ZDHHC19)

About Palmitoyltransferase ZDHHC19

Palmitoyltransferase ZDHHC19 (ZDHHC19) is a protein from Homo sapiens identified by UniProt accession Q8WVZ1, 309 residues long. MolForge cross-references it against 0 known binders and 143 disease associations.

Target properties

Protein name	Palmitoyltransferase ZDHHC19
UniProt accession	Q8WVZ1
Gene	ZDHHC19
Organism	Homo sapiens
Length	309 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (143)

Diseases linked to this target (Open Targets).

mean corpuscular hemoglobin concentration · score 0.42
mean corpuscular volume · score 0.40
mean corpuscular hemoglobin · score 0.39
erythrocyte count · score 0.37
Red cell distribution width · score 0.33
reticulocyte count · score 0.33
HbA1c measurement · score 0.28
red blood cell density measurement · score 0.27
reticulocyte measurement · score 0.27
platelet count · score 0.24

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8WVZ1-F1	alphafold	PREDICTED	78.03	—

Amino-acid sequence (309 residues)

MTLLTDATPL VKEPHPLPLV PRPWFLPSLF AAFNVVLLVF FSGLFFAFPC RWLAQNGEWA FPVITGSLFV LTFFSLVSLN FSDPGILHQG SAEQGPLTVH VVWVNHGAFR LQWCPKCCFH RPPRTYHCPW CNICVEDFDH HCKWVNNCIG HRNFRFFMLL VLSLCLYSGA MLVTCLIFLV RTTHLPFSTD KAIAIVVAVS AAGLLVPLSL LLLIQALSVS SADRTYKGKC RHLQGYNPFD QGCASNWYLT ICAPLGPKYM AEAVQLQRVV GPDWTSMPNL HPPMSPSALN PPAPTSGSLQ SREGTPGAW

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards