Kelch repeat and BTB domain-containing protein 7 (KBTBD7)
Homo sapiens — UniProt Q8WVZ9
Data last refreshed: (UniProt release unknown)
Key facts
Kelch repeat and BTB domain-containing protein 7 (KBTBD7) is a protein from Homo sapiens identified by UniProt accession Q8WVZ9, 684 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: Q8WVZ9; gene symbol KBTBD7.
- Organism: Homo sapiens.
- Length: 684 amino acids.
- Top disease associations (Open Targets): mean corpuscular hemoglobin concentration, mean corpuscular volume and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Kelch repeat and BTB domain-containing protein 7 |
|---|---|
| UniProt accession | Q8WVZ9 |
| Gene | KBTBD7 |
| Organism | Homo sapiens |
| Length | 684 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- mean corpuscular hemoglobin concentration · score 0.35
- mean corpuscular volume · score 0.30
- body height · score 0.28
- mean corpuscular hemoglobin · score 0.26
- multiple myeloma · score 0.22
- lung adenocarcinoma · score 0.18
- clear cell renal carcinoma · score 0.18
- endometrial cancer · score 0.18
- intraocular pressure measurement · score 0.13
- medulloblastoma · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WVZ9-F1 | alphafold | PREDICTED | 80.58 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WVZ9.
Amino-acid sequence (684 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KBTBD7?
The strongest Open Targets associations for KBTBD7 are mean corpuscular hemoglobin concentration, mean corpuscular volume, body height, mean corpuscular hemoglobin and multiple myeloma.
How long is the KBTBD7 protein?
The Homo sapiens KBTBD7 protein (UniProt Q8WVZ9) is 684 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WVZ9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WVZ9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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