LIM domain only protein 7 (LMO7)

Homo sapiens — UniProt Q8WWI1

Gene: LMO7Homo sapiensSwissProt reviewed

Data last refreshed: 2026-04-18 (UniProt release unknown)

Key facts

LIM domain only protein 7 (LMO7) is a protein from Homo sapiens identified by UniProt accession Q8WWI1, 1683 residues long. MolForge cross-references it against 0 known binders and 134 disease associations.

UniProt accession: Q8WWI1; gene symbol LMO7.
Organism: Homo sapiens.
Length: 1683 amino acids.
Top disease associations (Open Targets): intraocular pressure measurement, cancer and open-angle glaucoma.
3D structure: AlphaFold model available.

Target properties

Protein name	LIM domain only protein 7
UniProt accession	Q8WWI1
Gene	LMO7
Organism	Homo sapiens
Length	1683 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (134)

Diseases linked to this target (Open Targets).

intraocular pressure measurement · score 0.49
cancer · score 0.47
open-angle glaucoma · score 0.44
neurodegenerative disease · score 0.44
mean corpuscular hemoglobin · score 0.41
mean corpuscular volume · score 0.40
initial pursuit acceleration · score 0.38
mathematical ability · score 0.38
neurofibrillary tangles measurement · score 0.33
type 1 diabetes mellitus · score 0.33

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8WWI1-F1	alphafold	PREDICTED	50.42	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WWI1.

Amino-acid sequence (1683 residues)

MKKIRICHIF TFYSWMSYDV LFQRTELGAL EIWRQLICAH VCICVGWLYL RDRVCSKKDI ILRTEQNSGR TILIKAVTEK NFETKDFRAS LENGVLLCDL INKLKPGVIK KINRLSTPIA GLDNINVFLK ACEQIGLKEA QLFHPGDLQD LSNRVTVKQE ETDRRVKNVL ITLYWLGRKA QSNPYYNGPH LNLKAFENLL GQALTKALED SSFLKRSGRD SGYGDIWCPE RGEFLAPPRH HKREDSFESL DSLGSRSLTS CSSDITLRGG REGFESDTDS EFTFKMQDYN KDDMSYRRIS AVEPKTALPF NRFLPNKSRQ PSYVPAPLRK KKPDKHEDNR RSWASPVYTE ADGTFSSNQR RIWGTNVENW PTVQGTSKSS CYLEEEKAKT RSIPNIVKDD LYVRKLSPVM PNPGNAFDQF LPKCWTPEDV NWKRIKRETY KPWYKEFQGF SQFLLLQALQ TYSDDILSSE THTKIDPTSG PRLITRRKNL SYAPGYRRDD LEMAALDPDL ENDDFFVRKT GVFHANPYVL RAFEDFRKFS EQDDSVERDI ILQCREGELV LPDLEKDDMI VRRIPAQKKE VPLSGAPDRY HPVPFPEPWT LPPEIQAKFL CVFERTCPSK EKSNSCRILV PSYRQKKDDM LTRKIQSWKL GTTVPPISFT PGPCSEADLK RWEAIREASR LRHKKRLMVE RLFQKIYGEN GSKSMSDVSA EDVQNLRQLR YEEMQKIKSQ LKEQDQKWQD DLAKWKDRRK SYTSDLQKKK EEREEIEKQA LEKSKRSSKT FKEMLQDRES QNQKSTVPSR RRMYSFDDVL EEGKRPPTMT VSEASYQSER VEEKGATYPS EIPKEDSTTF AKREDRVTTE IQLPSQSPVE EQSPASLSSL RSRSTQMEST RVSASLPRSY RKTDTVRLTS VVTPRPFGSQ TRGISSLPRS YTMDDAWKYN GDVEDIKRTP NNVVSTPAPS PDASQLASSL SSQKEVAATE EDVTRLPSPT SPFSSLSQDQ AATSKATLSS TSGLDLMSES GEGEISPQRE VSRSQDQFSD MRISINQTPG KSLDFGFTIK WDIPGIFVAS VEAGSPAEFS QLQVDDEIIA INNTKFSYND SKEWEEAMAK AQETGHLVMD VRRYGKAGSP ETKWIDATSG IYNSEKSSNL SVTTDFSESL QSSNIESKEI NGIHDESNAF ESKASESISL KNLKRRSQFF EQGSSDSVVP DLPVPTISAP SRWVWDQEEE RKRQERWQKE QDRLLQEKYQ REQEKLREEW QRAKQEAERE NSKYLDEELM VLSSNSMSLT TREPSLATWE ATWSEGSKSS DREGTRAGEE ERRQPQEEVV HEDQGKKPQD QLVIERERKW EQQLQEEQEQ KRLQAEAEEQ KRPAEEQKRQ AEIERETSVR IYQYRRPVDS YDIPKTEEAS SGFLPGDRNK SRSTTELDDY STNKNGNNKY LDQIGNMTSS QRRSKKEQVP SGAELERQQI LQEMRKRTPL HNDNSWIRQR SASVNKEPVS LPGIMRRGES LDNLDSPRSN SWRQPPWLNQ PTGFYASSSV QDFSRPPPQL VSTSNRAYMR NPSSSVPPPS AGSVKTSTTG VATTQSPTPR SHSPSASQSG SQLRNRSVSG KRICSYCNNI LGKGAAMIIE SLGLCYHLHC FKCVACECDL GGSSSGAEVR IRNHQLYCND CYLRFKSGRP TAM

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with LMO7?

The strongest Open Targets associations for LMO7 are intraocular pressure measurement, cancer, open-angle glaucoma, neurodegenerative disease and mean corpuscular hemoglobin.

How long is the LMO7 protein?

The Homo sapiens LMO7 protein (UniProt Q8WWI1) is 1683 amino acids long.

Browse: Targets: L · all protein targets A–Z · drugs A–Z.

Sources

UniProtKB Q8WWI1 — name, gene, function, sequence, keywords (CC BY 4.0)
AlphaFold DB Q8WWI1 — predicted 3D structure (CC BY 4.0)
Open Targets Platform — disease associations and tractability (CC0)

How this page is built: methodology · editorial policy & corrections.

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