Ras association domain-containing protein 5 (RASSF5)
Homo sapiens — UniProt Q8WWW0
Data last refreshed: (UniProt release unknown)
Key facts
Ras association domain-containing protein 5 (RASSF5) is a protein from Homo sapiens identified by UniProt accession Q8WWW0, 418 residues long. MolForge cross-references it against 0 known binders and 218 disease associations.
- UniProt accession: Q8WWW0; gene symbol RASSF5.
- Organism: Homo sapiens.
- Length: 418 amino acids.
- Top disease associations (Open Targets): lymphocyte count, serum gamma-glutamyl transferase measurement and inflammatory bowel disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ras association domain-containing protein 5 |
|---|---|
| UniProt accession | Q8WWW0 |
| Gene | RASSF5 |
| Organism | Homo sapiens |
| Length | 418 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (218)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.30
- serum gamma-glutamyl transferase measurement · score 0.23
- inflammatory bowel disease · score 0.17
- total blood protein measurement · score 0.09
- neoplasm · score 0.09
- cancer · score 0.09
- common variable immunodeficiency · score 0.06
- immunodeficiency 72 with autoinflammation · score 0.06
- immunodeficiency 99 with hypogammaglobulinemia and autoimmune cytopenias · score 0.06
- immunodeficiency 105 · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WWW0-F1 | alphafold | PREDICTED | 67.32 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WWW0.
Amino-acid sequence (418 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RASSF5?
The strongest Open Targets associations for RASSF5 are lymphocyte count, serum gamma-glutamyl transferase measurement, inflammatory bowel disease, total blood protein measurement and neoplasm.
How long is the RASSF5 protein?
The Homo sapiens RASSF5 protein (UniProt Q8WWW0) is 418 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WWW0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WWW0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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