Prostate and testis expressed protein 1 (PATE1)
Homo sapiens — UniProt Q8WXA2
Data last refreshed: (UniProt release unknown)
Key facts
Prostate and testis expressed protein 1 (PATE1) is a protein from Homo sapiens identified by UniProt accession Q8WXA2, 126 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q8WXA2; gene symbol PATE1.
- Organism: Homo sapiens.
- Length: 126 amino acids.
- Top disease associations (Open Targets): Red cell distribution width, mean corpuscular volume and lymphocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Prostate and testis expressed protein 1 |
|---|---|
| UniProt accession | Q8WXA2 |
| Gene | PATE1 |
| Organism | Homo sapiens |
| Length | 126 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.05
- mean corpuscular volume · score 0.05
- lymphocyte count · score 0.04
- Reduced sperm motility · score 0.04
- vital capacity · score 0.03
- forced expiratory volume · score 0.02
- breast milk measurement · score 0.02
- protein measurement · score 0.02
- small cell lung carcinoma · score 0.02
- Abnormal sperm morphology · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WXA2-F1 | alphafold | PREDICTED | 80.10 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WXA2.
Amino-acid sequence (126 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PATE1?
The strongest Open Targets associations for PATE1 are Red cell distribution width, mean corpuscular volume, lymphocyte count, Reduced sperm motility and vital capacity.
How long is the PATE1 protein?
The Homo sapiens PATE1 protein (UniProt Q8WXA2) is 126 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WXA2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WXA2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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