COP9 signalosome complex subunit 9 (COPS9)
Homo sapiens — UniProt Q8WXC6
Data last refreshed: (UniProt release unknown)
Key facts
COP9 signalosome complex subunit 9 (COPS9) is a protein from Homo sapiens identified by UniProt accession Q8WXC6, 57 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: Q8WXC6; gene symbol COPS9.
- Organism: Homo sapiens.
- Length: 57 amino acids.
- Top disease associations (Open Targets): protein measurement, neuroticism measurement and head and neck squamous cell carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | COP9 signalosome complex subunit 9 |
|---|---|
| UniProt accession | Q8WXC6 |
| Gene | COPS9 |
| Organism | Homo sapiens |
| Length | 57 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.15
- neuroticism measurement · score 0.07
- head and neck squamous cell carcinoma · score 0.04
- hepatocellular carcinoma · score 0.03
- gut microbiome measurement · score 0.03
- multiple myeloma · score 0.01
- neoplasm · score 0.01
- cancer · score 0.01
- hyperplasia · score 0.00
- plasmacytoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WXC6-F1 | alphafold | PREDICTED | 62.42 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WXC6.
Amino-acid sequence (57 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with COPS9?
The strongest Open Targets associations for COPS9 are protein measurement, neuroticism measurement, head and neck squamous cell carcinoma, hepatocellular carcinoma and gut microbiome measurement.
How long is the COPS9 protein?
The Homo sapiens COPS9 protein (UniProt Q8WXC6) is 57 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WXC6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WXC6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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