Stonin-2 (STON2)
Homo sapiens — UniProt Q8WXE9
Data last refreshed: (UniProt release unknown)
Key facts
Stonin-2 (STON2) is a protein from Homo sapiens identified by UniProt accession Q8WXE9, 905 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.
- UniProt accession: Q8WXE9; gene symbol STON2.
- Organism: Homo sapiens.
- Length: 905 amino acids.
- Top disease associations (Open Targets): platelet count, refractive error measurement and platelet crit.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Stonin-2 |
|---|---|
| UniProt accession | Q8WXE9 |
| Gene | STON2 |
| Organism | Homo sapiens |
| Length | 905 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (56)
Diseases linked to this target (Open Targets).
- platelet count · score 0.53
- refractive error measurement · score 0.51
- platelet crit · score 0.45
- central corneal thickness · score 0.42
- glomerular filtration rate · score 0.40
- corneal topography · score 0.34
- platelet component distribution width · score 0.32
- male reproductive system disease · score 0.31
- mean corpuscular hemoglobin concentration · score 0.30
- erythrocyte count · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WXE9-F1 | alphafold | PREDICTED | 61.18 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WXE9.
Amino-acid sequence (905 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with STON2?
The strongest Open Targets associations for STON2 are platelet count, refractive error measurement, platelet crit, central corneal thickness and glomerular filtration rate.
How long is the STON2 protein?
The Homo sapiens STON2 protein (UniProt Q8WXE9) is 905 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WXE9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WXE9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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