Paraspeckle component 1 (PSPC1)
Homo sapiens — UniProt Q8WXF1
Data last refreshed: (UniProt release unknown)
Key facts
Paraspeckle component 1 (PSPC1) is a protein from Homo sapiens identified by UniProt accession Q8WXF1, 523 residues long. MolForge cross-references it against 0 known binders and 48 disease associations.
- UniProt accession: Q8WXF1; gene symbol PSPC1.
- Organism: Homo sapiens.
- Length: 523 amino acids.
- Top disease associations (Open Targets): body fat percentage, squamous cell lung carcinoma and calcium measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Paraspeckle component 1 |
|---|---|
| UniProt accession | Q8WXF1 |
| Gene | PSPC1 |
| Organism | Homo sapiens |
| Length | 523 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (48)
Diseases linked to this target (Open Targets).
- body fat percentage · score 0.28
- squamous cell lung carcinoma · score 0.20
- calcium measurement · score 0.13
- lean body mass · score 0.12
- fat body mass · score 0.12
- hepatocellular carcinoma · score 0.10
- neoplasm · score 0.09
- obstructive sleep apnea · score 0.08
- longitudinal alcohol consumption measurement · score 0.07
- alcohol use disorder measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WXF1-F1 | alphafold | PREDICTED | 72.78 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WXF1.
Amino-acid sequence (523 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PSPC1?
The strongest Open Targets associations for PSPC1 are body fat percentage, squamous cell lung carcinoma, calcium measurement, lean body mass and fat body mass.
How long is the PSPC1 protein?
The Homo sapiens PSPC1 protein (UniProt Q8WXF1) is 523 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WXF1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WXF1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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