Protein S100-Z (S100Z)

About Protein S100-Z

Protein S100-Z (S100Z) is a protein from Homo sapiens identified by UniProt accession Q8WXG8, 99 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.

Target properties

Protein name	Protein S100-Z
UniProt accession	Q8WXG8
Gene	S100Z
Organism	Homo sapiens
Length	99 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (28)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.41
red blood cell density measurement · score 0.11
erythrocyte count · score 0.08
proteinase-activated receptor 1 measurement · score 0.07
platelet component distribution width · score 0.05
mean corpuscular volume · score 0.04
drug use measurement · score 0.03
calcium measurement · score 0.02
neoplasm · score 0.02
chronic myelogenous leukemia · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8WXG8-F1	alphafold	PREDICTED	84.72	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WXG8.

Amino-acid sequence (99 residues)

MPTQLEMAMD TMIRIFHRYS GKERKRFKLS KGELKLLLQR ELTEFLSCQK ETQLVDKIVQ DLDANKDNEV DFNEFVVMVA ALTVACNDYF VEQLKKKGK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards