Ankyrin repeat and SOCS box protein 11 (ASB11)
Homo sapiens — UniProt Q8WXH4
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat and SOCS box protein 11 (ASB11) is a protein from Homo sapiens identified by UniProt accession Q8WXH4, 323 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.
- UniProt accession: Q8WXH4; gene symbol ASB11.
- Organism: Homo sapiens.
- Length: 323 amino acids.
- Top disease associations (Open Targets): clear cell renal carcinoma, acute myeloid leukemia and gastric carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat and SOCS box protein 11 |
|---|---|
| UniProt accession | Q8WXH4 |
| Gene | ASB11 |
| Organism | Homo sapiens |
| Length | 323 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (19)
Diseases linked to this target (Open Targets).
- clear cell renal carcinoma · score 0.18
- acute myeloid leukemia · score 0.10
- gastric carcinoma · score 0.05
- hepatocellular carcinoma · score 0.04
- 3-hydroxy-1-methylpropylmercapturic acid measurement · score 0.03
- melanoma · score 0.02
- acute myocardial infarction · score 0.02
- glioblastoma multiforme · score 0.02
- colorectal adenocarcinoma · score 0.01
- neoplasm · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WXH4-F1 | alphafold | PREDICTED | 87.68 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WXH4.
Amino-acid sequence (323 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ASB11?
The strongest Open Targets associations for ASB11 are clear cell renal carcinoma, acute myeloid leukemia, gastric carcinoma, hepatocellular carcinoma and 3-hydroxy-1-methylpropylmercapturic acid measurement.
How long is the ASB11 protein?
The Homo sapiens ASB11 protein (UniProt Q8WXH4) is 323 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WXH4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WXH4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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