Ankyrin repeat and SOCS box protein 17 (ASB17)
Homo sapiens — UniProt Q8WXJ9
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat and SOCS box protein 17 (ASB17) is a protein from Homo sapiens identified by UniProt accession Q8WXJ9, 295 residues long. MolForge cross-references it against 0 known binders and 75 disease associations.
- UniProt accession: Q8WXJ9; gene symbol ASB17.
- Organism: Homo sapiens.
- Length: 295 amino acids.
- Top disease associations (Open Targets): serum metabolite measurement, blood protein measurement and azoospermia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat and SOCS box protein 17 |
|---|---|
| UniProt accession | Q8WXJ9 |
| Gene | ASB17 |
| Organism | Homo sapiens |
| Length | 295 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (75)
Diseases linked to this target (Open Targets).
- serum metabolite measurement · score 0.25
- blood protein measurement · score 0.13
- azoospermia · score 0.09
- partial chromosome Y deletion · score 0.07
- male infertility with teratozoospermia due to single gene mutation · score 0.07
- spermatogenic failure 25 · score 0.06
- congenital bilateral absence of vas deferens · score 0.06
- spermatogenic failures 50 · score 0.06
- spermatogenic failure 48 · score 0.06
- spermatogenic failure 63 · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WXJ9-F1 | alphafold | PREDICTED | 85.89 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WXJ9.
Amino-acid sequence (295 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ASB17?
The strongest Open Targets associations for ASB17 are serum metabolite measurement, blood protein measurement, azoospermia, partial chromosome Y deletion and male infertility with teratozoospermia due to single gene mutation.
How long is the ASB17 protein?
The Homo sapiens ASB17 protein (UniProt Q8WXJ9) is 295 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WXJ9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WXJ9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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