Ankyrin repeat and SOCS box protein 15 (ASB15)
Homo sapiens — UniProt Q8WXK1
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat and SOCS box protein 15 (ASB15) is a protein from Homo sapiens identified by UniProt accession Q8WXK1, 588 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.
- UniProt accession: Q8WXK1; gene symbol ASB15.
- Organism: Homo sapiens.
- Length: 588 amino acids.
- Top disease associations (Open Targets): diastolic blood pressure, systolic blood pressure and clear cell renal carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat and SOCS box protein 15 |
|---|---|
| UniProt accession | Q8WXK1 |
| Gene | ASB15 |
| Organism | Homo sapiens |
| Length | 588 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (15)
Diseases linked to this target (Open Targets).
- diastolic blood pressure · score 0.24
- systolic blood pressure · score 0.24
- clear cell renal carcinoma · score 0.18
- mean platelet volume · score 0.11
- acute myeloid leukemia · score 0.10
- reticulocyte count · score 0.09
- mean corpuscular hemoglobin concentration · score 0.07
- reticulocyte measurement · score 0.07
- HbA1c measurement · score 0.07
- platelet crit · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WXK1-F1 | alphafold | PREDICTED | 87.58 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WXK1.
Amino-acid sequence (588 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ASB15?
The strongest Open Targets associations for ASB15 are diastolic blood pressure, systolic blood pressure, clear cell renal carcinoma, mean platelet volume and acute myeloid leukemia.
How long is the ASB15 protein?
The Homo sapiens ASB15 protein (UniProt Q8WXK1) is 588 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WXK1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WXK1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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