Ankyrin repeat and SOCS box protein 13 (ASB13)
Homo sapiens — UniProt Q8WXK3
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat and SOCS box protein 13 (ASB13) is a protein from Homo sapiens identified by UniProt accession Q8WXK3, 278 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q8WXK3; gene symbol ASB13.
- Organism: Homo sapiens.
- Length: 278 amino acids.
- Top disease associations (Open Targets): FEV/FVC ratio, pulse pressure measurement and waist-hip ratio.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat and SOCS box protein 13 |
|---|---|
| UniProt accession | Q8WXK3 |
| Gene | ASB13 |
| Organism | Homo sapiens |
| Length | 278 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- FEV/FVC ratio · score 0.29
- pulse pressure measurement · score 0.25
- waist-hip ratio · score 0.17
- BMI-adjusted waist circumference · score 0.15
- BMI-adjusted waist-hip ratio · score 0.14
- PHF-tau measurement · score 0.14
- heel bone mineral density · score 0.06
- drug use measurement · score 0.03
- age at menopause · score 0.03
- body height · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WXK3-F1 | alphafold | PREDICTED | 91.75 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WXK3.
Amino-acid sequence (278 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ASB13?
The strongest Open Targets associations for ASB13 are FEV/FVC ratio, pulse pressure measurement, waist-hip ratio, BMI-adjusted waist circumference and BMI-adjusted waist-hip ratio.
How long is the ASB13 protein?
The Homo sapiens ASB13 protein (UniProt Q8WXK3) is 278 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WXK3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WXK3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.