Carboxypeptidase A5 (CPA5)
Homo sapiens — UniProt Q8WXQ8
Data last refreshed: (UniProt release unknown)
Key facts
Carboxypeptidase A5 (CPA5) is a protein from Homo sapiens identified by UniProt accession Q8WXQ8, 436 residues long. MolForge cross-references it against 0 known binders and 96 disease associations.
- UniProt accession: Q8WXQ8; gene symbol CPA5.
- Organism: Homo sapiens.
- Length: 436 amino acids.
- Top disease associations (Open Targets): reticulocyte count, BMI-adjusted waist circumference and rheumatoid arthritis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Carboxypeptidase A5 |
|---|---|
| UniProt accession | Q8WXQ8 |
| Gene | CPA5 |
| Organism | Homo sapiens |
| Length | 436 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (96)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.18
- BMI-adjusted waist circumference · score 0.14
- rheumatoid arthritis · score 0.13
- genetic disorder · score 0.12
- Immature Reticulocyte Fraction Measurement · score 0.12
- familial atrial fibrillation · score 0.07
- Familial short QT syndrome · score 0.07
- Romano-Ward syndrome · score 0.07
- Brugada syndrome · score 0.07
- Arrhythmogenic right ventricular dysplasia · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WXQ8-F1 | alphafold | PREDICTED | 92.01 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WXQ8.
Amino-acid sequence (436 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CPA5?
The strongest Open Targets associations for CPA5 are reticulocyte count, BMI-adjusted waist circumference, rheumatoid arthritis, genetic disorder and Immature Reticulocyte Fraction Measurement.
How long is the CPA5 protein?
The Homo sapiens CPA5 protein (UniProt Q8WXQ8) is 436 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WXQ8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WXQ8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.