Myosin-IIIb (MYO3B)
Homo sapiens — UniProt Q8WXR4
Data last refreshed: (UniProt release unknown)
Key facts
Myosin-IIIb (MYO3B) is a protein from Homo sapiens identified by UniProt accession Q8WXR4, 1341 residues long. MolForge cross-references it against 4 known binders and 53 disease associations.
- UniProt accession: Q8WXR4; gene symbol MYO3B.
- Organism: Homo sapiens.
- Length: 1341 amino acids.
- Top disease associations (Open Targets): mathematical ability, gut microbiome measurement and BMI-adjusted waist-hip ratio.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Myosin-IIIb |
|---|---|
| UniProt accession | Q8WXR4 |
| Gene | MYO3B |
| Organism | Homo sapiens |
| Length | 1341 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (53)
Diseases linked to this target (Open Targets).
- mathematical ability · score 0.41
- gut microbiome measurement · score 0.40
- BMI-adjusted waist-hip ratio · score 0.36
- PHF-tau measurement · score 0.32
- neurofibrillary tangles measurement · score 0.31
- Bartholin gland disease · score 0.31
- abscess · score 0.31
- protein measurement · score 0.28
- lobe attachment · score 0.25
- BMI-adjusted hip circumference · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WXR4-F1 | alphafold | PREDICTED | 74.43 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WXR4.
Amino-acid sequence (1341 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MYO3B?
The strongest Open Targets associations for MYO3B are mathematical ability, gut microbiome measurement, BMI-adjusted waist-hip ratio, PHF-tau measurement and neurofibrillary tangles measurement.
How long is the MYO3B protein?
The Homo sapiens MYO3B protein (UniProt Q8WXR4) is 1341 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WXR4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WXR4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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