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DnaJ homolog subfamily C member 9 (DNAJC9)

Homo sapiens — UniProt Q8WXX5

Gene: DNAJC9Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

DnaJ homolog subfamily C member 9 (DNAJC9) is a protein from Homo sapiens identified by UniProt accession Q8WXX5, 260 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.

  • UniProt accession: Q8WXX5; gene symbol DNAJC9.
  • Organism: Homo sapiens.
  • Length: 260 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, PHF-tau measurement and hypertriglyceridemia 2.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameDnaJ homolog subfamily C member 9
UniProt accessionQ8WXX5
GeneDNAJC9
OrganismHomo sapiens
Length260 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (28)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.24
  • PHF-tau measurement · score 0.10
  • hypertriglyceridemia 2 · score 0.05
  • cholesterol-ester transfer protein deficiency · score 0.05
  • diastolic blood pressure · score 0.04
  • glomerular filtration rate · score 0.04
  • serum alanine aminotransferase measurement · score 0.04
  • cancer · score 0.04
  • total cholesterol measurement · score 0.04
  • reticulocyte measurement · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8WXX5-F1alphafoldPREDICTED85.36—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WXX5.

Amino-acid sequence (260 residues)

MGLLDLCEEV FGTADLYRVL GVRREASDGE VRRGYHKVSL QVHPDRVGEG DKEDATRRFQ ILGKVYSVLS DREQRAVYDE QGTVDEDSPV LTQDRDWEAY WRLLFKKISL EDIQAFEKTY KGSEEELADI KQAYLDFKGD MDQIMESVLC VQYTEEPRIR NIIQQAIDAG EVPSYNAFVK ESKQKMNARK RRAQEEAKEA EMSRKELGLD EGVDSLKAAI QSRQKDRQKE MDNFLAQMEA KYCKSSKGGG KKSALKKEKK

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with DNAJC9?

The strongest Open Targets associations for DNAJC9 are neurodegenerative disease, PHF-tau measurement, hypertriglyceridemia 2, cholesterol-ester transfer protein deficiency and diastolic blood pressure.

How long is the DNAJC9 protein?

The Homo sapiens DNAJC9 protein (UniProt Q8WXX5) is 260 amino acids long.

Browse: Targets: D · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8WXX5
GeneDNAJC9
OrganismHomo sapiens
Length260
Binders0
Diseases28
View on UniProt