Inhibitor of growth protein 5 (ING5)
Homo sapiens — UniProt Q8WYH8
Data last refreshed: (UniProt release unknown)
Key facts
Inhibitor of growth protein 5 (ING5) is a protein from Homo sapiens identified by UniProt accession Q8WYH8, 240 residues long. MolForge cross-references it against 0 known binders and 104 disease associations.
- UniProt accession: Q8WYH8; gene symbol ING5.
- Organism: Homo sapiens.
- Length: 240 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, hemoglobin measurement and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Inhibitor of growth protein 5 |
|---|---|
| UniProt accession | Q8WYH8 |
| Gene | ING5 |
| Organism | Homo sapiens |
| Length | 240 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (104)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.45
- hemoglobin measurement · score 0.29
- platelet count · score 0.29
- hematocrit · score 0.28
- mean platelet volume · score 0.27
- platelet component distribution width · score 0.26
- head and neck squamous cell carcinoma · score 0.19
- lung adenocarcinoma · score 0.18
- squamous cell lung carcinoma · score 0.18
- mean corpuscular hemoglobin concentration · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WYH8-F1 | alphafold | PREDICTED | 78.62 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WYH8.
Amino-acid sequence (240 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ING5?
The strongest Open Targets associations for ING5 are neurodegenerative disease, hemoglobin measurement, platelet count, hematocrit and mean platelet volume.
How long is the ING5 protein?
The Homo sapiens ING5 protein (UniProt Q8WYH8) is 240 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WYH8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WYH8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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