Contactin-associated protein-like 5 (CNTNAP5)
Homo sapiens — UniProt Q8WYK1
Data last refreshed: (UniProt release unknown)
Key facts
Contactin-associated protein-like 5 (CNTNAP5) is a protein from Homo sapiens identified by UniProt accession Q8WYK1, 1306 residues long. MolForge cross-references it against 0 known binders and 61 disease associations.
- UniProt accession: Q8WYK1; gene symbol CNTNAP5.
- Organism: Homo sapiens.
- Length: 1306 amino acids.
- Top disease associations (Open Targets): mathematical ability, self reported educational attainment and refractive error.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Contactin-associated protein-like 5 |
|---|---|
| UniProt accession | Q8WYK1 |
| Gene | CNTNAP5 |
| Organism | Homo sapiens |
| Length | 1306 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (61)
Diseases linked to this target (Open Targets).
- mathematical ability · score 0.44
- self reported educational attainment · score 0.44
- refractive error · score 0.30
- cognitive function measurement · score 0.30
- Abnormality of refraction · score 0.30
- unipolar depression · score 0.30
- bone density · score 0.29
- urate measurement · score 0.29
- posterior cortical atrophy · score 0.29
- chronotype measurement · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WYK1-F1 | alphafold | PREDICTED | 83.98 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WYK1.
Amino-acid sequence (1306 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CNTNAP5?
The strongest Open Targets associations for CNTNAP5 are mathematical ability, self reported educational attainment, refractive error, cognitive function measurement and Abnormality of refraction.
How long is the CNTNAP5 protein?
The Homo sapiens CNTNAP5 protein (UniProt Q8WYK1) is 1306 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WYK1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WYK1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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