Jun dimerization protein 2 (JDP2)
Homo sapiens — UniProt Q8WYK2
Data last refreshed: (UniProt release unknown)
Key facts
Jun dimerization protein 2 (JDP2) is a protein from Homo sapiens identified by UniProt accession Q8WYK2, 163 residues long. MolForge cross-references it against 0 known binders and 155 disease associations.
- UniProt accession: Q8WYK2; gene symbol JDP2.
- Organism: Homo sapiens.
- Length: 163 amino acids.
- Top disease associations (Open Targets): basal cell carcinoma, appendicular lean mass and basophil count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Jun dimerization protein 2 |
|---|---|
| UniProt accession | Q8WYK2 |
| Gene | JDP2 |
| Organism | Homo sapiens |
| Length | 163 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (155)
Diseases linked to this target (Open Targets).
- basal cell carcinoma · score 0.40
- appendicular lean mass · score 0.38
- basophil count · score 0.37
- basophil percentage of leukocytes · score 0.33
- non-melanoma skin carcinoma · score 0.32
- keratinocyte carcinoma · score 0.32
- skin neoplasm · score 0.32
- alcohol consumption measurement · score 0.27
- total blood protein measurement · score 0.24
- serum albumin measurement · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WYK2-F1 | alphafold | PREDICTED | 74.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WYK2.
Amino-acid sequence (163 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with JDP2?
The strongest Open Targets associations for JDP2 are basal cell carcinoma, appendicular lean mass, basophil count, basophil percentage of leukocytes and non-melanoma skin carcinoma.
How long is the JDP2 protein?
The Homo sapiens JDP2 protein (UniProt Q8WYK2) is 163 amino acids long.
Browse: Targets: J · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WYK2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WYK2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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