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Uncharacterized protein C22orf15 (C22orf15)

Homo sapiens — UniProt Q8WYQ4

Gene: C22orf15Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Uncharacterized protein C22orf15 (C22orf15) is a protein from Homo sapiens identified by UniProt accession Q8WYQ4, 148 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.

  • UniProt accession: Q8WYQ4; gene symbol C22orf15.
  • Organism: Homo sapiens.
  • Length: 148 amino acids.
  • Top disease associations (Open Targets): serum IgG glycosylation measurement, refractive error and lymphocyte count.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameUncharacterized protein C22orf15
UniProt accessionQ8WYQ4
GeneC22orf15
OrganismHomo sapiens
Length148 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (14)

Diseases linked to this target (Open Targets).

  • serum IgG glycosylation measurement · score 0.12
  • refractive error · score 0.12
  • lymphocyte count · score 0.07
  • lymphocyte percentage of leukocytes · score 0.06
  • erythrocyte count · score 0.03
  • ulcerative colitis · score 0.02
  • myocardial infarction · score 0.02
  • IgG digalactosylation measurement · score 0.02
  • IgG galactosylation measurement · score 0.02
  • IgG bisecting N-acetyl glucosamine measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8WYQ4-F1alphafoldPREDICTED76.13—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WYQ4.

Amino-acid sequence (148 residues)

MFIKVMFGAG CSVLVNTSCR LVNLTAHLRQ KAGLPPDATI ALLAEDGNLV SLEEDLKEGA SRAQTMGNSL LKERAIYVLV RIIKGEDMAS TRYESLLENL DDHYPELAEE LRRLSGLSSV GHNWRKRMGT RRGRHEQSPT SRPRKGPD

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with C22orf15?

The strongest Open Targets associations for C22orf15 are serum IgG glycosylation measurement, refractive error, lymphocyte count, lymphocyte percentage of leukocytes and erythrocyte count.

How long is the C22orf15 protein?

The Homo sapiens C22orf15 protein (UniProt Q8WYQ4) is 148 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8WYQ4
GeneC22orf15
OrganismHomo sapiens
Length148
Binders0
Diseases14
View on UniProt