Zinc finger CCHC domain-containing protein 14 (ZCCHC14)
Homo sapiens — UniProt Q8WYQ9
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger CCHC domain-containing protein 14 (ZCCHC14) is a protein from Homo sapiens identified by UniProt accession Q8WYQ9, 949 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.
- UniProt accession: Q8WYQ9; gene symbol ZCCHC14.
- Organism: Homo sapiens.
- Length: 949 amino acids.
- Top disease associations (Open Targets): neuroticism measurement, worry measurement and schizophrenia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger CCHC domain-containing protein 14 |
|---|---|
| UniProt accession | Q8WYQ9 |
| Gene | ZCCHC14 |
| Organism | Homo sapiens |
| Length | 949 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (52)
Diseases linked to this target (Open Targets).
- neuroticism measurement · score 0.42
- worry measurement · score 0.33
- schizophrenia · score 0.32
- unipolar depression · score 0.32
- feeling nervous measurement · score 0.31
- mathematical ability · score 0.30
- migraine disorder · score 0.29
- body height · score 0.29
- anxiety measurement · score 0.28
- wellbeing measurement · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WYQ9-F1 | alphafold | PREDICTED | 49.91 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WYQ9.
Amino-acid sequence (949 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZCCHC14?
The strongest Open Targets associations for ZCCHC14 are neuroticism measurement, worry measurement, schizophrenia, unipolar depression and feeling nervous measurement.
How long is the ZCCHC14 protein?
The Homo sapiens ZCCHC14 protein (UniProt Q8WYQ9) is 949 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WYQ9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WYQ9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.