CCR4-NOT transcription complex subunit 9 (CNOT9)
Homo sapiens — UniProt Q92600
Data last refreshed: (UniProt release unknown)
Key facts
CCR4-NOT transcription complex subunit 9 (CNOT9) is a protein from Homo sapiens identified by UniProt accession Q92600, 299 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.
- UniProt accession: Q92600; gene symbol CNOT9.
- Organism: Homo sapiens.
- Length: 299 amino acids.
- Top disease associations (Open Targets): melanoma, epilepsy and Intellectual disability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | CCR4-NOT transcription complex subunit 9 |
|---|---|
| UniProt accession | Q92600 |
| Gene | CNOT9 |
| Organism | Homo sapiens |
| Length | 299 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (51)
Diseases linked to this target (Open Targets).
- melanoma · score 0.47
- epilepsy · score 0.37
- Intellectual disability · score 0.37
- cutaneous melanoma · score 0.37
- Neurodevelopmental delay · score 0.34
- prostate adenocarcinoma · score 0.32
- bladder transitional cell carcinoma · score 0.32
- hepatocellular carcinoma · score 0.32
- gastric adenocarcinoma · score 0.32
- body height · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q92600-F1 | alphafold | PREDICTED | 92.41 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q92600.
Amino-acid sequence (299 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CNOT9?
The strongest Open Targets associations for CNOT9 are melanoma, epilepsy, Intellectual disability, cutaneous melanoma and Neurodevelopmental delay.
How long is the CNOT9 protein?
The Homo sapiens CNOT9 protein (UniProt Q92600) is 299 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q92600 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q92600 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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