Protein FAN (NSMAF)
Homo sapiens — UniProt Q92636
Data last refreshed: (UniProt release unknown)
Key facts
Protein FAN (NSMAF) is a protein from Homo sapiens identified by UniProt accession Q92636, 917 residues long. MolForge cross-references it against 0 known binders and 50 disease associations.
- UniProt accession: Q92636; gene symbol NSMAF.
- Organism: Homo sapiens.
- Length: 917 amino acids.
- Top disease associations (Open Targets): lymphocyte count, low density lipoprotein cholesterol measurement and total cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein FAN |
|---|---|
| UniProt accession | Q92636 |
| Gene | NSMAF |
| Organism | Homo sapiens |
| Length | 917 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (50)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.26
- low density lipoprotein cholesterol measurement · score 0.24
- total cholesterol measurement · score 0.23
- apolipoprotein B measurement · score 0.23
- mosaic loss of chromosome Y measurement · score 0.23
- triglyceride measurement · score 0.19
- basophil count · score 0.19
- sex hormone-binding globulin measurement · score 0.18
- aspartate aminotransferase measurement · score 0.09
- monocyte count · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q92636-F1 | alphafold | PREDICTED | 88.30 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q92636.
Amino-acid sequence (917 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NSMAF?
The strongest Open Targets associations for NSMAF are lymphocyte count, low density lipoprotein cholesterol measurement, total cholesterol measurement, apolipoprotein B measurement and mosaic loss of chromosome Y measurement.
How long is the NSMAF protein?
The Homo sapiens NSMAF protein (UniProt Q92636) is 917 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q92636 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q92636 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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