Tenascin-R (TNR)
Homo sapiens — UniProt Q92752
Data last refreshed: (UniProt release unknown)
Key facts
Tenascin-R (TNR) is a protein from Homo sapiens identified by UniProt accession Q92752, 1358 residues long. MolForge cross-references it against 0 known binders and 110 disease associations.
- UniProt accession: Q92752; gene symbol TNR.
- Organism: Homo sapiens.
- Length: 1358 amino acids.
- Top disease associations (Open Targets): neutrophil count, self reported educational attainment and attention deficit hyperactivity disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tenascin-R |
|---|---|
| UniProt accession | Q92752 |
| Gene | TNR |
| Organism | Homo sapiens |
| Length | 1358 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (110)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.38
- self reported educational attainment · score 0.30
- attention deficit hyperactivity disorder · score 0.29
- DNA methylation · score 0.28
- cognitive function measurement · score 0.27
- myeloid white cell count · score 0.27
- body height · score 0.26
- breast adenocarcinoma · score 0.20
- wet macular degeneration · score 0.20
- disease progression measurement · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q92752-F1 | alphafold | PREDICTED | 78.53 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q92752.
Amino-acid sequence (1358 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TNR?
The strongest Open Targets associations for TNR are neutrophil count, self reported educational attainment, attention deficit hyperactivity disorder, DNA methylation and cognitive function measurement.
How long is the TNR protein?
The Homo sapiens TNR protein (UniProt Q92752) is 1358 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q92752 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q92752 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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