Urocortin-3 (UCN3)
Homo sapiens — UniProt Q969E3
Data last refreshed: (UniProt release unknown)
Key facts
Urocortin-3 (UCN3) is a protein from Homo sapiens identified by UniProt accession Q969E3, 161 residues long. MolForge cross-references it against 0 known binders and 87 disease associations.
- UniProt accession: Q969E3; gene symbol UCN3.
- Organism: Homo sapiens.
- Length: 161 amino acids.
- Top disease associations (Open Targets): triglyceride measurement, sex hormone-binding globulin measurement and IGF-1 measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Urocortin-3 |
|---|---|
| UniProt accession | Q969E3 |
| Gene | UCN3 |
| Organism | Homo sapiens |
| Length | 161 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (87)
Diseases linked to this target (Open Targets).
- triglyceride measurement · score 0.27
- sex hormone-binding globulin measurement · score 0.21
- IGF-1 measurement · score 0.21
- alkaline phosphatase measurement · score 0.21
- neurodegenerative disease · score 0.21
- sleep duration · score 0.20
- type 2 diabetes mellitus · score 0.09
- MODY · score 0.08
- hyperinsulinism due to INSR deficiency · score 0.05
- Barrett's esophagus · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q969E3-F1 | alphafold | PREDICTED | 65.58 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q969E3.
Amino-acid sequence (161 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UCN3?
The strongest Open Targets associations for UCN3 are triglyceride measurement, sex hormone-binding globulin measurement, IGF-1 measurement, alkaline phosphatase measurement and neurodegenerative disease.
How long is the UCN3 protein?
The Homo sapiens UCN3 protein (UniProt Q969E3) is 161 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q969E3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q969E3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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