Riboflavin kinase (RFK)
Homo sapiens — UniProt Q969G6
Data last refreshed: (UniProt release unknown)
Key facts
Riboflavin kinase (RFK) is a protein from Homo sapiens identified by UniProt accession Q969G6, 155 residues long. MolForge cross-references it against 1 known binders and 45 disease associations.
- UniProt accession: Q969G6; gene symbol RFK.
- Organism: Homo sapiens.
- Length: 155 amino acids.
- Target class: Kinase.
- Top disease associations (Open Targets): neurodegenerative disease, refractive error measurement and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Riboflavin kinase |
|---|---|
| UniProt accession | Q969G6 |
| Gene | RFK |
| Organism | Homo sapiens |
| Length | 155 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Kinase (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (45)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- refractive error measurement · score 0.16
- body height · score 0.11
- neuritic plaque measurement · score 0.09
- P-selectin glycoprotein ligand 1 measurement · score 0.09
- D dimer measurement · score 0.08
- monocyte count · score 0.08
- metabolite measurement · score 0.08
- glucuronate measurement · score 0.06
- gut microbiome measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q969G6-F1 | alphafold | PREDICTED | 90.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q969G6.
Amino-acid sequence (155 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RFK?
The strongest Open Targets associations for RFK are neurodegenerative disease, refractive error measurement, body height, neuritic plaque measurement and P-selectin glycoprotein ligand 1 measurement.
How long is the RFK protein?
The Homo sapiens RFK protein (UniProt Q969G6) is 155 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q969G6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q969G6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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