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WW domain-binding protein 2 (WBP2)

Homo sapiens — UniProt Q969T9

Gene: WBP2Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

WW domain-binding protein 2 (WBP2) is a protein from Homo sapiens identified by UniProt accession Q969T9, 261 residues long. MolForge cross-references it against 0 known binders and 155 disease associations.

  • UniProt accession: Q969T9; gene symbol WBP2.
  • Organism: Homo sapiens.
  • Length: 261 amino acids.
  • Top disease associations (Open Targets): hearing loss, autosomal recessive, deafness and body mass index.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameWW domain-binding protein 2
UniProt accessionQ969T9
GeneWBP2
OrganismHomo sapiens
Length261 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (155)

Diseases linked to this target (Open Targets).

  • hearing loss, autosomal recessive · score 0.57
  • deafness · score 0.53
  • body mass index · score 0.25
  • reticulocyte count · score 0.24
  • platelet count · score 0.23
  • body weight · score 0.23
  • lean body mass · score 0.23
  • white matter hyperintensity measurement · score 0.22
  • fat body mass · score 0.22
  • body fat percentage · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q969T9-F1alphafoldPREDICTED72.18—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q969T9.

Amino-acid sequence (261 residues)

MALNKNHSEG GGVIVNNTES ILMSYDHVEL TFNDMKNVPE AFKGTKKGTV YLTPYRVIFL SKGKDAMQSF MMPFYLMKDC EIKQPVFGAN YIKGTVKAEA GGGWEGSASY KLTFTAGGAI EFGQRMLQVA SQASRGEVPS GAYGYSYMPS GAYVYPPPVA NGMYPCPPGY PYPPPPPEFY PGPPMMDGAM GYVQPPPPPY PGPMEPPVSG PDVPSTPAAE AKAAEAAASA YYNPGNPHNV YMPTSQPPPP PYYPPEDKKT Q

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with WBP2?

The strongest Open Targets associations for WBP2 are hearing loss, autosomal recessive, deafness, body mass index, reticulocyte count and platelet count.

How long is the WBP2 protein?

The Homo sapiens WBP2 protein (UniProt Q969T9) is 261 amino acids long.

Browse: Targets: W · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ969T9
GeneWBP2
OrganismHomo sapiens
Length261
Binders0
Diseases155
View on UniProt