Mitochondrial ubiquitin ligase activator of NFKB 1 (MUL1)
Homo sapiens — UniProt Q969V5
Data last refreshed: (UniProt release unknown)
Key facts
Mitochondrial ubiquitin ligase activator of NFKB 1 (MUL1) is a protein from Homo sapiens identified by UniProt accession Q969V5, 352 residues long. MolForge cross-references it against 0 known binders and 48 disease associations.
- UniProt accession: Q969V5; gene symbol MUL1.
- Organism: Homo sapiens.
- Length: 352 amino acids.
- Top disease associations (Open Targets): glioblastoma multiforme, body height and verbal-numerical reasoning measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mitochondrial ubiquitin ligase activator of NFKB 1 |
|---|---|
| UniProt accession | Q969V5 |
| Gene | MUL1 |
| Organism | Homo sapiens |
| Length | 352 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (48)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.23
- body height · score 0.17
- verbal-numerical reasoning measurement · score 0.15
- protein measurement · score 0.13
- esophageal cancer · score 0.10
- self reported educational attainment · score 0.08
- mathematical ability · score 0.08
- cognitive function measurement · score 0.08
- nonpapillary renal cell carcinoma · score 0.07
- hemoglobin measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q969V5-F1 | alphafold | PREDICTED | 89.89 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q969V5.
Amino-acid sequence (352 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MUL1?
The strongest Open Targets associations for MUL1 are glioblastoma multiforme, body height, verbal-numerical reasoning measurement, protein measurement and esophageal cancer.
How long is the MUL1 protein?
The Homo sapiens MUL1 protein (UniProt Q969V5) is 352 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q969V5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q969V5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.